Degradative Effect of Phenol on Endotoxin and Lipopolysaccharide Preparations from Serratia marcescens

Degradative effect of phenol on endotoxin and lipopolysaccharide preparations from Serratia marcescens.

It has been established that the well-known deproteinizing action of hot 45% aqueous phenol on whole cells or isolated and purified endotoxin of Serratia marcescens 08 is caused by the cleavage of a phenol-sensitive linkage within the lipid moiety. As a result of this degradation, both the lipopolysaccharide and simple protein fragments retained a part of the lipid moiety. Although not proceedi...

Effect of Lysol on Serratia marcescens

Chitinases from Serratia marcescens

Serratia marcescens is one of the most effective bacteria for degradation of chitin, a 1,4-β-linked polymer of N-acetyl-β-Dglucosamine (GlcNAc). Chitinolysis by S. marcescens involves at least four enzymes and a chitin-binding protein. Studies of the enzymology and the structures of the enzymes provide insight in how a natural set of chitinolytic enzymes may be built up. S. marcescens chitinase...

Some effects of polysaccharide preparations from Serratia marcescens and Aerobacter aerogenes on cells in tissue culture.

When certain polysaccharide fractions isolated from cultures of Serra@tia marcescens (6, 2), Aero bader aerogenes, or other Gram-negative bacteria (8) are injected in large doses into mice, symptoms very similar to those of shock occur. The animals are prostrated, their muscular response is much lower than normal, they breathe with difficulty, and the body temperature drops. Similar symp toms a...

R factors from Serratia marcescens.

In recent years, Serratia marcescens has become established in certain localities as an agent of hospital infection and cross-infection (Clayton & von Graevenitz, 1966; Wilfert, Barrett & Kass, 1968; Davis, Foltz & Blakemore, 1970; Wilkowske, Washington, Martin & Ritts, 1970). In general, strains of S. marcescens isolated from infective lesions differ from those from other sources in being non-...